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Schofferhofer hefeweizen beer11/10/2023 ![]() Contact your health-care provider immediately if you suspect that you have a medical problem. ![]() Content on this site is not intended to substitute for advice given by medical practitioner, pharmacist, or other licensed health-care professional. In the event of any safety concerns or for any other information about a product please carefully read any instructions provided on the label or packaging and contact the manufacturer. Please always read the labels, warnings, and directions provided with the product before using or consuming a product. We recommend that you do not solely rely on the information presented on our website. All information about the products on our website is provided for information purposes only. Actual product packaging and materials may contain more and/or different information than that shown on our website. To learn more about how and for what purposes Amazon uses personal information (such as Amazon Store order history), please visit our Privacy Notice.ĭisclaimer: While we work to ensure that product information on our website is correct, on occasion manufacturers may alter their ingredient lists. You can change your choices at any time by visiting Cookie Preferences, as described in the Cookie Notice. ![]() Click ‘Customise Cookies’ to decline these cookies, make more detailed choices, or learn more. Third parties use cookies for their purposes of displaying and measuring personalised ads, generating audience insights, and developing and improving products. This includes using first- and third-party cookies, which store or access standard device information such as a unique identifier. If you agree, we’ll also use cookies to complement your shopping experience across the Amazon stores as described in our Cookie Notice. We also use these cookies to understand how customers use our services (for example, by measuring site visits) so we can make improvements. We use cookies and similar tools that are necessary to enable you to make purchases, to enhance your shopping experiences and to provide our services, as detailed in our Cookie Notice.
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Euro to peso today11/10/2023 ![]() dollars by the bank processing the payment, not the date the foreign currency payment is received by the IRS. dollars is based on the date the foreign currency is converted to U.S. tax payments in a foreign currency, the exchange rate used by the IRS to convert the foreign currency into U.S. Note: The exchange rates referenced on this page do not apply when making payments of U.S. When valuing currency of a foreign country that uses multiple exchange rates, use the rate that applies to your specific facts and circumstances. Generally, it accepts any posted exchange rate that is used consistently. The Internal Revenue Service has no official exchange rate. See section 988 of the Internal Revenue Code and the regulations thereunder. dollar, make all income determinations in the QBU's functional currency, and where appropriate, translate such income or loss at the appropriate exchange rate.Ī taxpayer may also need to recognize foreign currency gain or loss on certain foreign currency transactions. If you have a QBU with a functional currency that is not the U.S. The only exception relates to some qualified business units (QBUs), which are generally allowed to use the currency of a foreign country. In general, use the exchange rate prevailing (i.e., the spot rate) when you receive, pay or accrue the item. dollars if you receive income or pay expenses in a foreign currency. Therefore, you must translate foreign currency into U.S. ![]() You must express the amounts you report on your U.S.
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Scarlet paintbrush plant witchcraft11/10/2023 ![]() ![]() ![]() Small shrublike perennials, or groups of erect, unbranched stems. Identification: Plants vary in size between about 6-79" (15-200 cm), Moist places, such as meadows and bogs elevations of 0.0-137783724.4 mils (0-214748364 µm)Īlpine and subalpine meadows in the Rocky Mountains and related western mountain ranges. Leaves are broadly lanceolate (lance-shaped), and entire (unlobed).įruits are ⅛-⅜" (6-12 mm) in size, containing seeds that are ¹/₃₂-¹/₁₆" (1.5-2 mm).Īmong sagebrush and grasses, pinyon/juniper and ponderosa pines between 3280-9842' (999-2999 m) Leaves are 1-2" (3-6 cm) long, lanceolate (lance-shaped) and entire (undivided), with sharp tips. Leaves are linear, long and narrow, usually entire (undivided), though sometimes upper leaves are lobed. Flowers are mostly bracts-modified leaves-which largely enclose greenish flowers. In addition to purple-magenta, pink-white, pink-magenta and crimson also occur. The flowerheads, 1-6" (3-15 cm) in size, are mostly bracts (modified leaves), colored crimson or scarlet the true flowers are small, green, and easily overlooked.Ī pink/purple hue rather than the more common strong red or red-orange colors. Bright red bracts (modified leaves) about 1¼" (3.4 cm) long mostly hide drab yellow-greenish flowers within. Plants occur in small clusters, with unbranched purplish or red stems.įlowerheads are ⅞-2" (2.5-5.2 cm) in size. Stems are green, becoming purplish with age. (Sometimes up to 6½' (2 m).) Initially grayish-green, stems and leaves become tinged with purple over time.ġ8-36" (45-91 cm) high, with unbranched or rarely branched stems. Plants are 12-40' (3.7-12 m) tall, and often branched. Yellow pine forest, foothills woodlands, chaparral, grasslandsĭry hills, woodlands, mesas, plains, high prairies, at elevations of 4800-10197' (1.5-3.1 km) Open summits, dry rocks, elevations 1.1-1.9 mi (1.7-3 km) Leaves are entire, not divided into lobes or forks. Linear, long and narrow, hairless on top and hairy beneath, often curled and almost tubular in shape. ⅜-1¾" (1-5 cm) long, mostly linear (long and narrow), sometimes forked. ¾-2" (2-6 cm) long, unlobed or forked into lobes. Flowers are orange-red or sometimes yellow-green in color, appearing from March to June.įlowers are greenish, with a bright scarlet tinge largely hidden by the bracts, specialized leaves that are red-orange or sometimes yellowish in color. Each flower is ½-⅞" (1.5-2.5 cm) in size, surrounded with bracts (modified leaves) of similar size. They are yellowish to dull red.įlower clusters are 1-8" (3-20 cm). Bracts-modified leaves-appear under each flower, and are ¼-¾" (6.3-19 mm) long. Yellow to pale green or purplish red in color, appearing in June. Plants are up to 20" (50 cm) in height, covered with fuzzy white hairs. Torrey Pines State Park, La Jolla, Californiaġ2-24" (30-60 cm) tall, multiply branched, coated with a "felt" of white to gray, branched hairs.Woolly Indian paintbrush (Castilleja foliolosa) Click the species name for the article onĬobwebby Indian paintbrush (Castilleja arachnoidea) This table compares several species of Indian paintbrush. Mark is perhaps the world's foremost expert on this genus. This dependency on surrounding plants makes paintbrushes difficult toĬastillejas, don't miss Mark Egger's superb Indian paintbrushes are hemiparasitic-they derive some of their nutrients by attaching to The flowerheads resemble both brightly daubed paintbrushes and, in groups, dancing flames. TheyĪre most commonly known as Indian paintbrush, and also called prairie-fire. (1744-1793), a name chosen by his teacher, botanist José Celestino Mutis. The genus takes its name from Spanish botanist Domingo Castillejo Genus, comprised of about 200 species, is native to the Americas, northern Asia, and part of Siberia. ![]() Named for Spanish botanist Domingo Castillejo Vascular plants-plants with a “circulatory system” for delivering water and nutrientsįlowering plants, also known as angiospermsĭicotyledons-plants with two initial seed leavesĪromatic herbs and shrubs, including lavender, lilac, olive, jasmine, ash, teak, snapdragon, sesame, psyllium, garden sage, mint, basil, and rosemary FloraFinder uses cookies only for correct operation.
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Glycolysis pathway11/10/2023 Khib was initially identified as a novel post-translational modification (PTM) on histones in HeLa and mouse testis cells by Dai et al. ![]() PTMs are taking part in various biological processes and closely associated with the pathogenesis of various tumors. Previous studies have identified more than 400 different types of PTMs that play crucial roles in numerous cellular functions, including cellular proliferation, metabolism, and signal transduction. But protein post-translational modifications (PTMs), involving specific chemical alterations, have resulted in the formation of approximately two million protein entities. Human genes constitute approximately 30,000 entities, of which approximatively 2% encode proteins. Consequently, it is crucial to explore the pathogenesis of OACC and identify new targeted treatments. However, these interventions have a significant negative impact on patient’s quality of life, including changes in saliva volume, chewing ability, facial appearance, and verbal expression. The standard treatment options for OACC in clinical practice involve surgical intervention and radiotherapy. To date, drug treatment for OACC have not been standardized and the progress on targeted treatment has been sluggish. Recurrence rates within the 5-to-10-year range vary from 30 to 75%. The survival rate of OACC within a span of 15 to 20 years is approximately 23 to 40%. OACC is distinguished by a significant occurrence of local–regional recurrence and distant metastasis. Due to its rarity, limited research has been conducted on the pathogenesis and treatment of OACC. Oral adenoid cystic carcinoma (OACC), accounting for less than 2% of malignant head and neck tumors (3–4.5 cases per million annually worldwide), is a rare tumor of oral cancer. In February 2022, the China National Cancer Center indicated that the incidence of oral cancer in 2016 was 3.78 cases per 100,000 individuals annually. These findings may provide new therapeutic options of OACC. Khib may play a significant role in the mechanism of OACC progression by influencing the enzyme activity of the glycolysis pathway. Khib may increase the catalytic efficiency to promote glycolysis pathway and favor OACC progression. GAPDH of K254, ENO of K228, and PGK1 of K323 were modified by Khib in OACC-T. DEPs and DHMPs were strongly associated to glycolysis pathway. ResultsĬompared OACC-tumor samples (OACC-T) with the adjacent normal samples (OACC-N), there were 3243 of the DEPs and 2011 Khib sites were identified on 764 proteins (DHMPs). We investigated the DEPs (differentially expressed proteins) and DHMPs between OACC-T and OACC-N using LC–MS/MS-based quantitative proteomics and using several bioinformatics methods, including GO enrichment analysis, KEGG pathway analysis, subcellular localization prediction, MEA (motif enrichment analysis), and PPI (protein–protein interaction networks) to illustrate how Khib modification interfere with OACC evolution. The objective of this study is to investigate the impact of Khib on OACC and its potential as a targeted therapeutic intervention. Without NAD +, the reaction in step 6 cannot proceed and glycolysis slows or stops. In an environment without oxygen, an alternate pathway (fermentation) can provide the oxidation of NADH to NAD +.Oral adenoid cystic carcinoma (OACC) has high rates of both local–regional recurrence and distant metastasis. However, if there is no oxygen available, NADH is not converted back into NAD +. If oxygen is available in the system, the NADH will be converted readily back into NAD + by the later processes in aerobic cellular respiration. If NAD + is not available, the second half of glycolysis slows down or stops. Thus, NADH must be continuously converted back into NAD + in order to keep this step going. However, the continuation of the reaction depends upon the availability of NAD +. ![]() NADH contains more energy than NAD +, and is therefore a desired product from this reaction. \), you will notice that during step 6, NAD + is converted into NADH.
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Inkdrop snowflake11/10/2023 Document templates, workflow automation, smart snippets, and Python scripting let you make the app your own. Like Drafts, it’s highly configurable and offers strong automation features. It also supports Fountain, a markup language for screenwriters, and TaskPaper’s format for plain text to-do lists. Editorialĭesktop-class plain text productivity on iOS.Įditorial is a powerful text editor for iOS that offers excellent Markdown support. It’s a highly customizable way to compose in Markdown. Each entry can be tagged, flagged, and archived as needed.īasic Markdown syntax highlighting is offered, as is a preview pane. Cost: free download, subscription from $2.99/monthĭrafts 5 is the ultimate capture tool: an inbox for text and Markdown content that can be routed to other apps through powerful actions.A number of popular cloud storage solutions are supported. Unlike Byword, iA Writer supports images, tables, and content blocks. ![]() A light gray background, monospaced font, and blue cursor are used. It offers more features than Byword, and a little less simplicity.įocus mode fades surrounding lines of text to emphasize what you’re typing. IA Writer is a distraction-free Markdown editor that places the focus on your content. iA Writer offers a unique writing experience that lets you concentrate and clarify your message.
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Neo4j 325m eurazeo 2b crichtontechcrunch11/9/2023 ![]() And it’s this awareness of, again, speaking to a company like ComplyAdvantage who are saying, “Look, we’re building our own knowledge graph knowledge base.” It’s just like this is really becoming a thing in peoples’ heads and they’re looking for solutions. So the solution is a graph database in this case. What is more sophisticated is when you can just take raw data and preserve older relationships between your data points, and they can run analysis on top of this. We see across our board – importantly from the portfolio side, but also when we speak to other companies – the importance again of databases, and more importantly, being able to do more sophisticated analysis. And then, super excitingly, is the continued expansion, now in particular going into the graph data science space, where analytics is becoming a very relevant piece to the whole equation. ![]() So you’ve got a perfect combination here, whereby you’ve got the market coming together and you have a very strong leader, superior technology, where experts were pointing two/three years ahead of time in terms of the sophistication. What really struck a chord with us when we looked deeper into Neo4j, and started to do market work, is just the superiority of the offering. ![]() We also know quite a few of your existing investors, so they’ve been raving about it and really pointing toward graph databases, which is one of the key areas that, as an investor, you look into – in terms of the market opportunity out there. Yann, who leads our strategy, had the first interaction with Emil. Nathalie Kornhoff-Brüls: So Neo4j, or more importantly, I would say that the database – and then specifically, the graph database space – has been on our radar for over a year. Tell us about the first time you came across Neo4j and your first impressions.
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Greenfoot breakout11/9/2023 ![]() From teenage boys to Adults, Carti hoodies are best For men of every age. You can find a huge variety of different designs and Colors so Select the one that suits best to your requirements. Playboi Carti hoodies are the best winter Hoodies because of two things “Quality and Quality”. Yes, we assure hoodies of excellent quality. These hoodies are skin-friendly and your long-term partner. ![]() Which are the most Popular Playboi Carti Hoodies? You can select your size easily as various Sizes are available.Ĭarti hoodies are for different casual occasions like friends’ parties, hangouts, dinner dates, and a long walk in the cold evening.These hoodies are soft and Super Comfortable.Carti hoodies stand out and are one of the best choices for Men because: You just need to invest in them for once and wear them for ages. ![]() The Playboi Hoodies collection is extraordinary. Playboi carti bunny hoodie: A minimal simple and the most comfortable hoodie From the carti hoodies collection.Playboi carti neon tour hoodie: An excellent choice For street style lovers.Playboi carti vlone hoodie: A perfect winter clothing item as it’s super warm, stylish, and Comfortable.A skeleton hoodie playboi carti can be worn on different occasions including Halloween parties.Playboi carti black cat hoodie: The best hoodie for everyday style.Some of the most Popular Carti hoodies are: Our hardworking team of Designers makes sure you get some extraordinary clothing items. Unlike other big clothing brands, Playboi doesn’t cost you an arm or a leg.
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Perfect layers .911/9/2023 On the bottom of the browse window is a slider that adjusts the thumbnail size in the preview window. On the left you have a favorite’s location along with a sources pane with a list of common locations, folders pane with a tree view of the current source, and a filters pane that you can use to filter your images based on criteria such as star rating or flagging. On the right you have an info pane with information on your image, metadata, and photo history. When you open up the Browser you have a main preview window in the middle where you can see your images in thumbnail form where you can control the number and size of the images you are previewing. The Browser is built much in the same way as you would have in a host application although there no true cataloging capability you now do have the ability to rate and label your images. For more information about pricing and what the differences are between these editions, check out the comparison page at onOne’s website. Perfect Photo Suite comes in a Basic Edition which is a complete standalone photo editing solution or a Premium Edition which also integrates with Adobe, Lightroom, Photoshop, Photoshop Elements, and Apple Aperture. Perfect Resize is used for increasing or changing your image size without loss or detail. The Perfect Mask tools have now been moved into the Perfect Layers module for better efficiency. Perfect Layers is for combining and blending images without Photoshop. Perfect Portrait is for all of your portrait retouching. Perfect B&W is for converting your images to black and white. Perfect Effects can be used for stylizing your images. There is a Browse module that gives you the ability to locate the files that you want to work on, Perfect Enhance that will provide you with the capability to enhance your images. There are seven areas in Perfect Photo Suite. It contains everything you need to handle even fairly complex photographic post processing tasks. While it still integrates with Adobe Photoshop, Adobe Photoshop Elements, and Apple Aperture, it is also a complete standalone photo editor. You can also purchase them separately on the website.Perfect Photo Suite 9 is the latest release of products from onOne Software. (Remember, each ruler gives you 4 widths, so that’s 12 border sizes in all.) ![]() But if you are working on a big project or multiple albums and want to make fast work of your matting,  it’s easy enough to use and justifies the $29.95 price tag for the set of three. I’m not a heavy-duty scrapbooker, and I’m not really partial to cutting square or rectangular mats for every photo and text block. So, it’s a great tool if you do a lot of matting. Perfect Layers would have been (ahem) perfect for that job! I remember back in the day when I was matting text- it was always a little irregular, and I always cut a mat to go with it. It turned out OK, but between the bumpy texture of the image and the thinness of the paper, it was hard to feel the “lip.” I had to line it up more by sight than feel. Lastly, I used it on a stenciled image that was done on text-weight paper. But really, if your goal is to get your mats done quickly, it’s worth wasting some scraps of paper. Now, because you glue the photo or image down on your paper first, and then cut it away, there is a little more waste than what I’m used to. Let’s take a closer look at the tools before we get started. Well this sounds right up my alley! To tell the truth, I don’t measure mats, anyway- I’m an “eyeball it” kinda gal.  Simply follow the tool edge along all sides of your picture or project, and you have a perfectly matted or framed result!  Each tool has stainless-steel edging for durability and smoothness of cutting. Using a standard craft knife blade, just cut along the outside of the Perfect Layers tool.  The tool hooks onto the edge of the image, giving the precise border measurement you want! Perfect Layers is designed with a patented “catch lip†that simply “bumps” up along the picture.  Lisa loved this item, and was quoted as saying, “This is one of my favorite tools we sell for scrapbooking!† Using Perfect Layers, you can cut from 1/16 of an inch (very thin borders), up to 1 inch (very bold borders), WITH NO MEASURING REQUIRED!!įor over a decade, Perfect Layers has been an essential tool for paper crafters. You may have seen it on QVC as a Customer Top-Rated Item presented by Scrapbooking Guru, Lisa Bearnson. Perfect Layers is a MUST if you want to create perfect borders, frames and layered effects on your scrapbook pages, cards, or any paper crafting project. ![]() The website describes Perfect Layers thus: But do they work, and are they still a handy tool to have on your craft table? Time to find out! ![]() Perfect Layers is a craft tool that has been around since the early days of scrapbooking- a set of clear acrylic rulers that have “bumpers” on the underside that make it possible to cut mats (or layers) without measuring.
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Hotel casa maya cancun reviews11/9/2023 ![]() ![]() Other than different color lounges, having pillows and probably better drink service, the beach was no different than the one we were on all week. She said that she wanted to tell us how different our vacation would be if we were Elite members! Wouldn't you think that a resort would treat ALL guests the same? They have a separate section of their beach designated for their members only! All week, I think we saw 2 couples there. She said that the only people at the resort were exchanges for RCI & Interval and then their Elite members. We told her that we were not interested in buying another timeshare. Once the check-in paperwork was completed ( it went fairly quick), we were told that we could not have our room keys until we sat with the timeshare representative! We were shown to a table in the lobby bar and waited almost 20 minutes before she arrived. First, as our airport transportation ( USA Transfers- great!) pulled up to the front door, the timeshare rep was already waiting for us! They had my last name wrong so she "allowed" me to go to the check-in counter. This resort is the one that we will not return to. We have been to Cancun three consecutive years and have stayed at a different resort each year. We did not want our rooms cleaned daily and they respected that only cleaning on the day we requested. They always needed to go find someone else to help us. I've always been told to start with the positive first, so.most all the staff were very friendly and tried to be helpful, although the majority did not speak or understand English. We just returned from Casa Maya last night. Logically we know that they are doing their job but we were on vacation and had already decided what we wanted to spend for it. As timeshare owners we are very familiar with "upgrade" sales tactics and we resented being held "hostage" while waiting 30 minutes for our room to be ready and to get our keys. We refused this conversation since we were stressed and exhausted after enduring a full day of travel. One drawback was the pressure we received from the time share representative who tried to speak with us immediately after we registered. After becoming familiar with the area we rented our car at the resort which proved to be convenient, inexpensive and efficient. For adventure we rode the public buses for a couple of days to "check out the area" without the stress of driving. We had a one bedroom unit with a fully equipped kitchen in order to enjoy a lot of our meals "at home". Accommodations and activities are extensive. Their beach has beautiful white sand (water shoes not needed) and warm water. Casa Maya is a very clean and friendly resort providing daily maid service if wanted. We used their private shuttle service from the airport which cost a little more than a group shuttle service but reduced the ride time considerably.
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Medical grant writer salary11/9/2023 ![]() ![]() You may help change lives by writing proposals for grants that serve a good cause. Only 40% of ob-gyns said they felt valued.There are several opportunities available for a rewarding career as a grant writer. The other top five specialties all fell below 50% on that metric. Meanwhile, just 52% of pediatrician respondents reported feeling valued by their organization. Rounding out the top six most burned-out specialties are hospital medicine (59%), family medicine (58%), pediatrics (55%), obstetrics and gynecology (54%), and internal medicine (52%). Higher pay far surpassed all other reasons for becoming a travel nurse, followed by dissatisfaction with management.Īn American Medical Association survey released in August ranked emergency medicine physicians as the top specialty affected by burnout, with 62% of respondents reporting symptoms. In the 2022 Nurse Salary Research Report, 29% of nurses said they were considering leaving the profession, a steep rise from the 11% who were considering such a move in the 2020 survey.Īmong the respondents, 4% said they work as travel nurses, and 62% of those became travel nurses in 2020 or 2021. Only 4% of residents would prefer to practice in a community of 25,000 or less, underscoring the challenges rural communities face when recruiting new physicians. Eighty-two percent of residents said "lifestyle" is very important to them as they consider a first practice, followed by "adequate personal time" (80%), "good financial package" (78%) and geographic location (76%). Lifestyle and personal time are of the highest importance to residents considering job opportunities. The majority of residents (81%) indicated that they sometimes, often, or always experienced feelings of burnout during their residency, which is likely a key reason why many expressed second thoughts about their choice of a career, the survey found. Only 64% of female physicians said they would choose medicine again as a career compared to 73% of males. Feelings of angst and frustration are expressed in many of the written comments residents included in the survey.įemale physicians were more likely to express reservations about their career choice than were males. Of the 30% who indicated they would choose a field other than healthcare, many are troubled by the length, expense, intensity and stress of their training, and by the conditions that may greet them in their first professional practice. Forty percent of general internal medicine residents are IMGs, according to the American Medical Association Physician Masterfile. This may be due in part to the fact that IMGs are overrepresented in some areas of primary care, particularly internal medicine, the survey found. ![]() graduates said they received 51 or more job solicitations during their training, compared to only 67% of IMGs. Eighty-one percent of male residents said they received 51 or more job solicitations during their training, while 61% said they received 100 or more meanwhile, 72% of female residents said they received 51 or more job solicitations, while 51% said they received 100 or more.Įighty percent of U.S. As demand for physicians rises, the supply of physicians is being inhibited by an insufficient number of residency positions, physician aging and physician burnout, the latter of which was exacerbated by the pandemic.īoth male and female residents reportedly received numerous job solicitations during their training, though male residents reported receiving more solicitations than female residents. This marks a strong rebound from where things were in the middle of the COVID-19 pandemic – in 2021, only 30% of residents indicated they received 100 or more job solicitations.Īnd yet, despite the robust job market, 30% of residents indicated they would not choose medicine if they had their careers to do over, the highest number since the survey was first conducted.ĭemand for physicians is being driven by a variety of factors, including population growth, population aging, and prevailing population ill-health. Seventy-eight percent of residents received 51 or more job solicitations during their training, also the highest number since the survey was first conducted. AMN Healthcare's 2023 Survey of Final-Year Medical Residents showed that this is the highest number since the survey was first conducted in 1991. The job market is strong for medical residents, with the majority (56%) in a new survey saying they received 100 or more job solicitations during their training. Photo: ER Productions Limited/Getty Images |